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Islet Biology Lab - Uncovering the Mechanisms of Diabetes
We focus on understanding pancreatic islet function and survival in health and diabetes to prevent or slow progression in susceptible individuals.
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The Translational Research Laboratory for Diabetes, INSERM UMR1190, directed by Professor Pattou, is a research unit whose main focus is the treatment of diabetes. This is done primarily through islet transplantation, a form of cell therapy for the treatment of unstable type 1 diabetes, and through the biological study of islets of Langherans in glycemic regulation. Our laboratory is located on the campus of the University Hospital of Lille, in the Research Center of the Faculty of Medicine.
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The mission of the Human Islet Research Network (HIRN) is to better understand how human beta cells are lost in Type 1 Diabetes and to find innovative strategies to protect or replace functional beta cell mass in diabetic patients.
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DRIVE aims to improve pancreatic islet transplant therapy for diabetes mellitus, a chronic disease characterised by high blood sugar due to a shortage of insulin. Transplant of insulin-producing pancreatic islets restores tight natural control of blood sugar, eliminating the need for multiple daily injections of insulin, that ultimately affect patient’s quality of life.
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