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HSP27 Scientific Resource Guide | HSP27
Heat Shock Protein 27 (HSP27) information database. A resource for all HSP27 structure, isoform, function, disease relevance, and inhibitor information.
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Heat Shock Protein 90 (HSP90) information database. A resource for all HSP90 structure, isoform, function, disease relevance, and inhibitor information.
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HSP60 Introduction | HSP60
Heat shock protein 60 (Hsp60) is one of the most conserved proteins and is present in all three “primary kingdoms”: eukaryotes, eubacteria, and Archaea.
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The 78 kDa glucose-regulated protein 78 (Grp78), also known as immunoglobulin heavy-chain binding protein or binding-immunoglobulin protein (BiP), is a multifunctional protein which belongs to the huge HSP70 family of molecular chaperones 1, 2. Grp78/BiP is constitutively expressed in the ER lumen where it assists in ER proteostasis which is critically involved in the folding …
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Hsp47, also known as Serpin H1, is an ER-resident procollagen-specific molecular chaperone essential for the biosynthesis and structural assembly of collagen 1-3. Beside its role in collagen biosynthesis, Hsp47 represents an essential factor in the mammalian Golgi stress response 4. Hsp47 belongs to clade H of the SERPIN superfamily of proteinase inhibitors, but it does …
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The heme oxygenases (HOs) are key enzymes in the oxidative degradation of heme to biliverdin (biliverdin IXα), carbon monoxide (CO), and ferrous iron (Fe2+) 1. In mammals, two main isoforms are expressed: HO-1 (also known as Hsp32) and HO-2. While HO-2 is constitutively expressed under basic requirements in the majority of human tissues, HO-1 represents …
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