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Moriarty Lab - Moriarty Lab
What we study We are an infectious diseases research laboratory studying several fundamental mechanisms underlying blood borne dissemination of bacterial pathogens. The major model organism we study is Borrelia burgdorferi, the causative agent of Lyme disease. The Moriarty lab studies multiple features of dissemination, using techniques from genetics, molecular and cell biology, biochemistry, biophysics and […]
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The COVID-19 host genetics initiative aims to provide support and an analytical network for studies that are broadly interested in identifying genetic determinants of COVID-19 susceptibility and severity. Such discoveries could help to generate hypotheses for **** repurposing, identify individuals at unusually high or low risk, and contribute to global knowledge of the biology of SARS-CoV-2 infection and disease.
Home | CRL: Cytokine Receptor Lab
At the Cytokine Receptor Lab, we combine basic research with technology development. Using growing insights in cytokine receptor signalling, we are developing the MAPPIT toolbox, a technology platform that allows studying molecular interactions in intact mammalian cells.
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Our group uses developmental genetics and systems biology methods to study gene networks controlling diversification of cell types during development. Specifically, we are interested in how the discrete subsets of muscle and heart cells are specified and how their distinct properties are acquired in normal and in pathological conditions. To address these problems we are using Drosophila as a model system.
Qi Chen Lab - University of California, Riverside School of Medicine
Dr. Qi Chen is a reproductive & developmental biologist at University of California, Riverside School of Medicine. We study **** RNAs and their roles in mediating intergenerational and transgenerational epigenetic inheritance. We are also interested in studying the molecular mechanisms of Symmetry-breaking in mammalian early embryo. Our recent works focus on **** tsRNAs (tRNA-derived small RNAs) and its role in epigenetic memory, showing that **** tsRNAs act as a type of paternal epigetic factor that contribute to intergenerational inheritance of an acquired metabolic disorder. Research from his lab add to the growing body of inheritable factors beyond DNA sequences, l...